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Manager Alex Cora said Casas suffered a significant knee injury during Friday's game against the Twins, Mac Cerullo of the Boston Herald reports.

Casas stepped on first base awkwardly while trying to beat out a throw in the second inning. He left the field on a stretcher and was transported to a hospital. The Red Sox will know more about the extent of his injury Saturday, but it doesn't seem like the 25-year-old will be back in the lineup anytime soon. Romy Gonzalez will likely take over as Boston's primary first baseman going forward.

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