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A Big Ten showdown will take place on Saturday when Michigan State travels to Lincoln, Nebraska, to face the Cornhuskers. Nebraska leads the all-time series 9-4 against Michigan State, with the first meeting between the programs dating back to 1914.

Nebraska is coming off its first loss of the season against Michigan at home after starting the 2025 campaign 3-0 with wins over Cincinnati, Akron and Houston Christian. During the loss to the Wolverines at home, the Cornhuskers allowed 10 unanswered points coming out of halftime, and that proved to be the difference in a 30-27 loss.

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As for Michigan State, the Spartans are also coming off their bye week. Michigan State suffered its first loss against USC last month after starting the season with wins over Western Michigan, Boston College and Youngstown State. The 45-31 setback to USC marked the third consecutive game that Michigan State allowed more than 40 points against a Power Four opponent.

Here is everything you need to know ahead of Michigan State's matchup against Nebraska.

Where to watch Nebraska vs. Michigan State live

Date: Saturday, Oct. 4 | Time: 4 p.m. ET
Location: Memorial Stadium -- Lincoln, Nebraska
TV: FS1 | Stream: Fubo (Try for free)

Nebraska vs. Michigan State: Need to know

Nebraska's defense has been elite: Nebraska enters this game allowing just 75.8 yards per game through the air, which ranks No. 1 in the FBS. The Cornhuskers have held their opponents to 105 yards passing or less in each of their first four games this season, which is the second-longest streak in FBS history. Miami's 2005 squad held opponents to under 105 yards passing in five consecutive games.

Matchup of star quarterbacks: This game will feature two of the best signal-callers in the conference: Nebraska's Dylan Raiola and Michigan State's Aidan Chiles. Raiola, the former five-star quarterback prospect from the 2024 recruiting cycle, has thrown for 11 touchdowns (with just one interception) during his team's first four games. Chiles, the former Oregon State transfer, has thrown for nine touchdowns with just one interception.

Big moment for Nebraska: The Cornhuskers have a prime opportunity to bounce back in a big way after the loss to Michigan. Furthermore, Nebraska has a favorable schedule for the remainder of the season, with only one game (No. 7 Penn State) remaining against a ranked opponent. This week's game against Michigan State and a matchup at home against USC will go a long way toward deciding how Year 3 of the Matt Rhule era will end.

Nebraska vs. Michigan State prediction, pick

Nebraska's secondary has been elite this season. If the Cornhuskers can get pressure on Chiles and jump out to a lead early, Nebraska should be able to control the flow of this game at home. Raiola is off to a hot start to his sophomore season. Look for Nebraska to come out and make a statement after a heartbreaking loss against Michigan last month. Pick: Nebraska -11.5