Oregon vs. Indiana prediction, odds, spread, time: 2025 Week 7 college football picks by proven model
The SportsLine projection model has revealed its Oregon Ducks vs. Indiana Hoosiers picks for Saturday on CBS and Paramount+
Undefeated Big Ten rivals will battle as the No. 3 Oregon Ducks (5-0, 2-0) host the No. 7 Indiana Hoosiers (5-0, 2-0) in a college football Week 7 showdown on CBS and Paramount+. Dante Moore and the Ducks secured a 30-24 double-overtime win against Penn State before their Week 6 bye. Fernando Mendoza and the Hoosiers are also coming out of the bye week, with their last game being a 20-15 win against Iowa. Indiana is 3-2 against the spread, while Oregon is 4-1 ATS.
Kickoff from Autzen Stadium is set for 3:30 p.m. ET. The Ducks are 7-point favorites in the latest Indiana vs. Oregon odds, and the over/under for total points scored is 53.5, down half a point from the opener. Before making any Oregon vs. Indiana picks, be sure to see what the SportsLine projection model has to say. Be sure to watch this game on CBS or Paramount+, where new users can get a free one-week trial. Sign up here.
New users can also target the DraftKings promo code, which offers $200 in bonus bets instantly if your initial $5 bet wins:
The model simulates every FBS game 10,000 times. Since its inception, it has generated a betting profit of well over $2,000 for $100 players on its top-rated college spread football picks, and is a profitable 38-25 combined on money-line and over/under college football picks since the beginning of 2024. Anybody following its college football betting picks at sportsbooks and on betting sites could have seen strong returns.
Now, the model has zeroed in on Oregon vs. Indiana. You can head to SportsLine now to see its picks. Here are several college football odds and betting lines for Indiana vs. Oregon in Week 7:
Indiana vs. Oregon spread | Oregon -7 at DraftKings Sportsbook |
Indiana vs. Oregon over/under | 53.5 points |
Indiana vs. Oregon money line | Oregon -290, Indiana +234 |
Indiana vs. Oregon picks | |
Indiana vs. Oregon streaming | Paramount+ (Get 7 days free) |
Why Indiana can cover
The Hoosiers have one of the toughest defenses in the nation, holding opponents to 256.3 total yards per game. While Oregon poses the biggest threat out of any of their previous adversaries, Indiana can also run up the scoreboard since Mendoza is completing 73% of his passes with 16 touchdowns and just one interception. The Hoosiers also know how to stand up to ranked competition, blowing out No. 17 Illinois 63-10 earlier this season. See which team to back at SportsLine.
Why Oregon can cover
The Ducks are 3-1-1 ATS this season and 22-1 at home in the Dan Lanning era. The defense is allowing 316.1 total yards per game but just 19.4 points, and held Penn State quarterback Drew Allar to just 137 passing yards in Week 5. Heisman Trophy favorite Moore has a 79.8 completion percentage and a 14-1 TD-INT ratio, while freshman running back Dierre Hill Jr. is averaging 10.4 yards per carry with two touchdowns on the ground. See which team to back at SportsLine.
New users can also check out the latest FanDuel promo code and get $300 in bonus bets instantly at FanDuel if your $5 bet wins.
How to make Oregon vs. Indiana picks
For Indiana vs. Oregon in Week 7, the model is leaning over the total, and also says one side of the spread hits in almost 60% of simulations. See what it is at SportsLine.
Who wins Indiana vs. Oregon, and which side of the spread hits almost 60% of the time? Visit SportsLine now to see which side of the Oregon vs. Indiana spread you need to jump, all from the model that is a combined 38-25 on top-rated picks since 2024, and find out.
