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The top-ranked and defending national champion Ohio State Buckeyes look to stay perfect both this season and all-time against Rutgers when they take on the Scarlet Knights on Saturday. Rutgers is coming off a 35-20 win over Maryland on Nov. 8, while Ohio State cruised to a 48-10 win over UCLA last Saturday. The Scarlet Knights (5-5, 2-5 Big Ten), who have lost five of seven, are 1-3 on the road this season. The Buckeyes (10-0, 7-0 Big Ten), who have won 14 in a row, are 6-0 on their home field this season. Star Ohio State receivers Carnell Tate and Jeremiah Smith have both been ruled out. 

Kickoff from Ohio Stadium in Columbus, Ohio, is at noon ET. After opening at -32.5, the Buckeyes are now 30.5-point favorites in the latest Ohio State vs. Rutgers odds, while the over/under for total points scored is 53.5, down two points from the opening line as an adjustment to OSU's star receivers being out. Before making any Rutgers vs. Ohio State picks, check out the college football predictions from the SportsLine Projection Model

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The model simulates every FBS game 10,000 times, and it is profitable on its top-rated money-line and over/under picks since the beginning of the 2024 season. Anybody following those college football betting picks at sportsbooks and on betting sites could have seen strong returns.

Now, the model has set its sights on Rutgers vs. Ohio State. You can visit SportsLine now to see the picks. Here are the FBS college football odds and trends for Ohio State vs. Rutgers:

Rutgers vs. Ohio State spread

Ohio State -30.5 at DraftKings Sportsbook

Rutgers vs. Ohio State over/under

53.5 points

Rutgers vs. Ohio State money line 

Ohio State -8333, Rutgers +2200

Rutgers vs. Ohio State picks

See picks at SportsLine

Rutgers vs. Ohio State streaming 

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How to make Rutgers vs. Ohio State picks

SportsLine's model is going Over on the total (54.5). Points could be hard to come by for Rutgers, though the Scarlet Knights have hit the 27-point plateau in two of their past three games. Ohio State, meanwhile, has scored at least 34 points in its last six games, so the Buckeyes can do a lot of the heavy lifting to get over the total against a Rutgers squad that ranks 16th in the Big Ten in scoring defense.

The model projects 55 combined points, making the Over the value side.

The model also says one side of the spread hits nearly 60% of the time. You can only get that pick at SportsLine. 

So who wins Rutgers vs. Ohio State, and which side of the spread hits nearly 60% of the time? Visit SportsLine now to see which side of the Rutgers vs. Ohio State spread to jump on, all from the advanced model that has simulated this game 10,000 times, and find out.