College football line movements for Week 13, including No. 15 USC at No. 7 Oregon

Two longtime rivals on the West Coast meet in a pivotal Big Ten matchup that has major College Football Playoff implications when the No. 7 Oregon Ducks host the No. 15 USC Trojans at Autzen Stadium in Eugene, Ore. 

The Ducks (9-1, 6-1 in the Big Ten) and Trojans (8-2, 6-1) are both technically alive for a Big Ten title berth as they're both tied with Michigan (8-2, 6-1). Losses by either No. 1 Ohio State or No. 2 Indiana could cause some chaos atop the conference standings. 

But this USC-Oregon matchup is more about CFP positioning as the Ducks may very well clinch a postseason berth with a win while the Trojans can't afford a third loss on the year. 

Bet college football Week 13, including USC at Oregon, at DraftKings Sportsbook, where new users get $200 in bonus bets and three months of NBA League Pass. Click here to sign up:

USC will need to solve its issues on the road to stay alive in the CFP hunt. Since coach Lincoln Riley arrived in Los Angeles in 2022, the Trojans are 1-6 when playing a ranked team on the road. That includes defeats at No. 23 Illinois and No. 13 Notre Dame this season. Over its last 20 games facing ranked opponents on the road, USC is 2-18. In addition, the Trojans haven't won in Autzen Stadium since 2011.

Top sportsbooks have made Oregon a 10.5-point favorite over USC. The line has risen from -8.

So what should you make of all that line movement? Is it a market correction or an overreaction? Here's a look at the Oregon-USC point spread, as well as the line movement on four other Week 13 games. All times Eastern.

No. 22 Missouri at No. 8 Oklahoma (noon)

Open: Oklahoma -10
Current: Oklahoma -5.5

This line was moving even before it was announced that Missouri QB Beau Pribula (ankle) will play on Saturday. That Pribula was upgraded to questionable helped move the line past -7, but it should be noted that Oklahoma has an elite defense and can make life tough on a QB who may be operating at less than 100% mobility. The Sooners' defense ranks second in the country in sacks per game (3.70). Oklahoma does face the possibility of a letdown one week after upsetting Alabama, but the value is now on the Sooners.

Bet Week 13 college football games at FanDuel Sportsbook, where new users get $150 in bonus bets. Click here:

Ball State at Toledo (2 p.m.)

Open: Toledo -23
Current: Toledo -28

This game features the biggest line movement of the week, with sportsbooks now making the Rockets four-touchdown favorites. The movement makes sense. Toledo is a perfect 5-0 at home this season, winning by an average of 40.0 points per game. Conversely, Ball State is 0-5 on the road this year, losing by 26.4 points a game. The Rockets boast the No. 1 offense and defense in the MAC, while the Cardinals are 12th (out of 13) in offense and 10th in defense. Toledo bettors won't get the best number, but it may not matter.

Marshall at Appalachian State (2:30 p.m.)

Open: Marshall -2
Current: Marshall -5.5

This point spread shift is a reaction to Appalachian State's recent slide. The Mountaineers have lost four in a row and are coming off a 58-10 blowout loss against James Madison. Though they are at home, they have dropped their last two home contests to Coastal Carolina and Georgia Southern. Meanwhile, the Thundering Herd (5-5, 3-3 in Sun Belt) still have incentive on Saturday; one more win makes Marshall bowl-eligible.

Bet college football at Caesars Sportsbook, where new users get 20 100% profit boost tokens. Click here to get started:

No. 15 USC at No. 7 Oregon (3:30 p.m.)

Open: Oregon -8
Current: Oregon -10.5

This point spread has jumped quickly since open and got to 10.5. USC is hardly a bad team, but Oregon presents a tough challenge for the Trojans given the Ducks' ability to run the ball offensively and stop the pass defensively. This may force USC into a game it's not particularly comfortable with. Oregon bettors have missed the best number at this point, but the Ducks still seem to be the right side.

New Mexico at Air Force (7 p.m.)

Open: Air Force -1
Current: New Mexico -3.5

This line has completely flipped. The biggest reason? A key injury as Air Force quarterback Liam Szarka is out for the season with a broken arm. The Falcons now turn the offense over to Kemper Hodges, a 6-foot, 245-pound converted fullback who has taken just 39 snaps this year. Air Force scored nine points with Hodges in for Szarka in a loss to UConn. While a lot of focus will be on Szarka's injury, the Lobos (7-3) are in the midst of one of the best turnaround seasons in college football this year.