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The first College Football Playoff rankings were revealed on Tuesday, and the Alabama Crimson Tide will enter Saturday's SEC showdown against the LSU Tigers ranked No. 4. The Crimson Tide have dominated this rivalry in recent years, winning eight of the last 10 meetings with LSU. According to the latest Week 11 college football odds, the Crimson Tide are favored by 10.5 points at home, while the over/under for LSU vs. Alabama is 49.5 points. However, SportsLine's advanced computer model is backing LSU, which will be playing its first game since firing head coach Brian Kelly, to cover the spread in 58% of simulations. 

The model is also backing Washington (-11) to cover the spread on the road against Wisconsin, while the Over (41.5) hits 69% of the time in Oregon vs. Iowa. Before locking in your Week 11 college football picks, be sure to check out the top college football betting picks from SportsLine's advanced computer model. 

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The model simulates every FBS game 10,000 times. Since its inception, it has generated a betting profit of over $2,000 for $100 players on its top-rated college football spread picks. Anybody following its college football betting picks at sportsbooks and on betting sites could have seen strong returns.

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Week 11 college football best bets for Saturday, Nov. 8 (odds subject to change): 

  • LSU (+10.5) vs. Alabama
  • Washington (-11) vs. Wisconsin
  • Oregon vs. Iowa: Over 41.5 points

Combining the model's three picks into a Week 11 college football parlay would result in a payout of +596 (risk $100 to win $596). Bet it now at Caesars Sportsbook: 

LSU +10.5 vs. Alabama

The Tigers are in the midst of a disappointing season, which ultimately led to the firing of head coach Brian Kelly. However, LSU still features one of the nation's top-ranked scoring defenses. In fact, the Tigers are giving up only 18.9 points per game, which ranks 22nd in college football. SportsLine's model is calling for an Alabama win on Saturday, but is expecting LSU to stay within the double-digit spread in 58% of its simulations. 

Washington -11 vs. Wisconsin

The Badgers limp into Saturday's matchup having lost each of their last six games. Meanwhile, Washington is 6-2 this season and 10-2 in its past 12 games played in November. Wisconsin's offense has been abysmal in recent weeks, scoring seven or fewer points in each of its last three games. The Badgers have failed to score more than 10 points in their last five games, and SportsLine's model is projecting Wisconsin's offense will struggle again on Saturday, leading to a comfortable victory for Washington, as the Huskies cover the spread in 53% of simulations. 

Over 41.5 points in Oregon vs. Iowa

The Ducks feature the fifth-ranked scoring offense in the nation with an average of 41.2 points per game. Iowa's offense has been prolific in recent weeks as well, scoring 37 or more points in two of its last three games. The total has gone Over in four of Iowa's last six games, and SportsLine's model is expecting an entertaining affair in this Big Ten battle. The model is projecting these teams will combine for 52 points, helping the Over hit in 69% of simulations.

Want more Week 11 college football picks?

You've seen the model's Week 11 college football best bets for Saturday. Now, get against the spread, total and money line picks for every Week 11 CFB game here, all from the model that's simulated every game 10,000 times.