Arkansas vs. Michigan State odds, prediction, line, time: 2025 college basketball picks from proven model

John Calipari and the No. 14 Arkansas Razorbacks travel to East Lansing to take on Tom Izzo and the No. 22 Michigan State Spartans in a battle of legendary coaches on Saturday. Michigan State beat Colgate 80-69 in its opener, while Arkansas beat Southern 109-77 on Monday. Trevon Brazile led the way for Arkansas with 25 points, while Jaxon Kohler paced Michigan State with 16 points. 

Tipoff from the Breslin Center is set for 7 p.m. ET. The Spartans are 1.5-point favorites in the latest Michigan State vs. Arkansas odds, while the over/under is 155.5. Before making any Arkansas vs. Michigan State picks, check out the men's college basketball predictions and betting advice from the SportsLine Projection Model.

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The SportsLine Projection Model simulates every college basketball game 10,000 times and has returned over $2,200 in betting profit for $100 players on its top-rated college basketball picks over the past three seasons. Anyone following its college basketball betting advice at sportsbooks and on betting apps could have seen huge returns.

Now, the model has simulated Michigan State vs. Arkansas 10,000 times and just revealed its coveted men's college basketball picks and betting predictions. You can head to SportsLine now to see the model's picks. Here are several men's college basketball odds and men's college basketball betting lines for Arkansas vs. Michigan State:

How to make Michigan State vs. Arkansas picks

SportsLine's model has simulated Arkansas vs. Michigan State 10,000 times and revealed its picks. It is going Under on the total, saying these teams will combine for 148 points. No player is projected to score more than 12 points in the simulations, with Darius Acuff Jr. (12.4 ppg) projected to lead all scorers. 

Arkansas gave up an average of 71.4 points per game last season, while Michigan State ranked 34th nationally in that category, giving up 67.1. 

The model also says one side of the spread hits in well over 60% of simulations. You can go to SportsLine to see the model's picks. 

So who wins Arkansas vs. Michigan State, and which side of the spread hits well over 60% of the time? Visit SportsLine now to see which side of the spread to back, all from the advanced model that is up more than $2,200 on top-rated college basketball picks, and find out.