Marquee matchups are set to unfold all day as part of the Week 10 NFL schedule, including pivotal games like Vikings vs. Packers, Cowboys vs. 49ers and Bengals vs. Steelers. According to the latest Week 10 NFL odds, the Bengals are favored by 3.5 pionts at home against the Steelers. The Cowboys vs. 49ers game features an over/under of 56 points, the highest among the Week 10 NFL totals. Other notable NFL spreads on Sunday include Bills vs. Jets (+7.5), Packers vs. Vikings (+2.5) and 49ers vs. Cowboys (+4.5). Bet on every NFL game with the latest DraftKings promo code, where new users get $200 in bonus bets plus 3 free months of NBA League Pass after making a $5 wager:
Below you'll find the NFL betting odds for every Week 10 matchup. You can find the SportsLine Projection Model's NFL betting advice for Week 10 here. Trade $25+ at Kalshi using the best Kalshi promo code CBSSPORTS55 and get a $55 bonus:
** Odds provided by DraftKings are subject to change **
Sunday, November 15
Kansas City Chiefs vs. Atlanta Falcons
Spread: Chiefs -3
Moneyline: Chiefs (-166), Falcons (+140)
Total: 47.5
Houston Texans vs. Cleveland Browns
Spread: Texans -4.5
Moneyline: Texans (-238), Browns (+195)
Total: 40.5
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Minnesota Vikings vs. Green Bay Packers
Spread: Packers -2.5
Moneyline: Packers (-148), Vikings (+124)
Total: 42.5
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Jacksonville Jaguars vs. Tennessee Titans
Spread: Jaguars -10.5
Moneyline: Jaguars (-750), Titans (+525)
Total: 46.5
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Miami Dolphins vs. Indianapolis Colts
Spread: Colts -4.5
Moneyline: Colts (-218), Dolphins (+180)
Total: 37.5
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Carolina Panthers vs. New Orleans Saints
Spread: Saints -2.5
Moneyline: Saints (-135), Panthers (+114)
Total: 48.5
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Buffalo Bills vs. New York Jets
Spread: Bills -8.5
Moneyline: Bills (-425), Jets (+330)
Total: 50.5
Seattle Seahawks vs. Las Vegas Raiders
Spread: Seahawks -6.5
Moneyline: Seahawks (-305), Raiders (+245)
Total: 40.5
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Los Angeles Rams vs. Arizona Cardinals
Spread: Rams -9.5
Moneyline: Rams (-500), Cardinals (+380)
Total: 39.5
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San Francisco 49ers vs. Dallas Cowboys
Spread: 49ers -4.5
Moneyline: 49ers (-205), Cowboys (+170)
Total: 55.5
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Pittsburgh Steelers vs. Cincinnati Bengals
Spread: Bengals -3.5
Moneyline: Bengals (-180), Steelers (+150)
Total: 49.5
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Monday, November 16
Los Angeles Chargers vs. Baltimore Ravens
Spread: Ravens -4.5
Moneyline: Ravens (-218), Chargers (+180)
Total: 38.5
Week 10 byes: Bears, Broncos, Eagles and Buccaneers.
