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Week 5 of the NFL regular season is underway on Sunday, perfect for using the latest FanDuel promo code, which gives new users $300 in bonus bets if their first wager of $5 or more wins. The Tampa Bay Buccaneers (3-1) and the Seattle Seahawks (3-1) play at 4:05 p.m. ET. According to the latest NFL odds at FanDuel, the Seahawks are -189 money line favorites (risk $189 to win $100), while the Buccaneers are +157 underdogs.

SportsLine's model is projecting the Buccaneers to cover the spread in 53% of simulations. The model's best bets also include the over of 47 total points in the Commanders vs. Chargers game. Meanwhile, SportsLine's model has the over (49.5) cashing in the Patriots vs. Bills game in 59% of simulations. Claim the latest FanDuel promo code here:

Check out our FanDuel promo code review for full details.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model is on a sizzling 39-20 run on top-rated picks dating back to 2024. Anybody following its NFL betting picks at sportsbooks and on betting sites could have seen strong returns.

Best Sunday picks

  • Buccaneers (+3.5) vs. Seahawks (-110)
  • Commanders vs. Chargers: Over 47.5 total points (-105)
  • Patriots vs. Bills: Over 49.5 total points (-112)

Combining the model's three picks into a three-leg parlay at FanDuel would result in a payout of +605 (risk $100 to win $605). Bet it at FanDuel here:

Buccaneers (+3.5) vs. Seahawks (-110)

The Bucs have played in one-possession games in the first four games, taking away wins in three of those outings. Tampa Bay owns a 2-0 ATS record as the away team and road underdog. While the Bucs will be without Bucky Irving and Mike Evans offensively, the Seahawks plan to be without Devon Witherspoon, DeMarcus Lawrence, and Julian Love on defense. SportsLine's model has Tampa Bay covering the spread in 53% of simulations. 

Commanders vs. Chargers: Over 47.5 total points (-105)

The Chargers are eighth in the NFL in total offense (356.3). Justin Herbert ranks fourth in the NFL in passing yards (1,063) with seven passing touchdowns. Receiver Quentin Johnston is fifth in receiving yards (337) and tied for third in receiving touchdowns (4). Meanwhile, Washington has Jayden Daniels back under center after missing the last two games with a knee injury. Daniels has 433 passing yards and three passing touchdowns in those two outings. Deebo Samuel leads the way in Washington with 204 receiving yards and two touchdowns. SportsLine's model projects the over hitting 57% of simulations. 

Patriots vs. Bills: Over 49.5 total points (-112)

Buffalo enters this game with the second-ranked total offense (404) and scoring offense (33.3) in the NFL. That unit has scored over 30 points in every game this season. Meanwhile, New England has poured in 30-plus points in two of their last three games. The over has cleared in three of the last four Bills games. Meanwhile, the over cashed in two New England games in 2025. SportsLine's model predicts these teams will combine for 54 total points and the over hitting in 59% of simulations.

Want more NFL picks?

You've seen the model's best bets for Sunday. Now, get against the spread, total and money-line picks for every NFL game here, all from the model that's simulated every game 10,000 times.