49ers vs. Panthers anytime touchdown scorer picks, betting odds, predictions: Back George Kittle on MNF

Week 12 will close out with the San Francisco 49ers hosting the Carolina Panthers on Monday Night Football. Both teams are in the NFC playoff hunt with San Francisco at 7-4 and Carolina at 6-5 on the season, so it's a matchup with significant postseason implications. 49ers tight end George Kittle has historically been a big game performer and he's scored three touchdowns in his last two games, but the latest 49ers vs. Panthers anytime TD scorer odds still list Kittle as high as +140 to score. The SportsLine Projection Model predicts he scores 0.73 touchdowns on average and that pricing makes him one of our top MNF anytime touchdown scorer picks.

Targeting NFL player props is one way to approach NFL odds at online sports betting sites for Monday Night Football in Week 12. With NFL props available for almost every player in Panthers vs. 49ers at top online sportsbooks, SportsLine's proven computer model can help you find value to add to your San Francisco vs. Carolina NFL picks. 

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The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 12 on a sizzling 48-33 run on top-rated picks dating back to 2024. Anybody following its NFL betting picks at sportsbooks and on betting sites could have seen strong returns. Now, it has revealed its top anytime touchdown picks for 49ers vs. Panthers.

Best Monday Night Football anytime TD prop picks:

• George Kittle, 49ers (+140)
• Brian Robinson Jr., 49ers (+425)
• Chuba Hubbard, Panthers (+550)

Parlay these picks for +6500 odds with the latest DraftKings promo code and get $200 in bonus bets if your first $5 wager wins and three months free NBA League Pass:

George Kittle, 49ers (+140, bet365)

Kittle has missed five games so far this season, but when he's been active he's been heavily involved in San Francisco's offensive plans. He has 27 catches for 251 yards and five touchdowns in six games this season and has scored in four of the five games where he's been targeted at least four times. The Carolina defense has generally been solid this season, but tight ends do have 58 catches for 718 yards and five touchdowns against the Panthers. Kittle scores 0.73 touchdowns on average in the model's simulations and these odds imply a 41.7% chance to score. Use the latest bet365 bonus code to find this price and get $150 in bonus bets after your first $5 wager win or lose.

Brian Robinson Jr., 49ers (+425, bet365)

Christian McCaffrey is the NFL's biggest workhorse with 267 touches over his first 11 games. However, Kyle Shanahan has been making a concerted effort to get Robinson involved, particularly in short-yardage situations. He's had eight carries in each of his last two games and has scored a touchdown in two of San Francisco's last three outings. The model predicts that he scores 0.32 touchdowns on average while these odds imply a 19.1% chance to score. Get $150 in bonus bets after your first $5 wager win or lose.

Chuba Hubbard, Panthers (+550, FanDuel)

Hubbard has been the unfortunate victim of circumstance this season, as Rico Dowdle broke through as one of the league's most dynamic backs while Hubbard was injured. He's healthy now, but Dowdle has become the workhorse in Carolina. However, Hubbard was a big-money signing not that long ago and as the more physically imposing back between the two, it wouldn't be out of the question for him to receive some goal-line usage. The model predicts 0.31 touchdowns on average while these odds imply a 15.4% chance to score. Use the latest FanDuel promo code to find this price and get $150 in bonus bets if your first $5 wager wins.

Want more Monday Night Football picks?

You've seen the model's NFL anytime touchdown prop picks for several players in Panthers vs. 49ers. Now, get NFL projections for every player prop at SportsLine.

Need more from SportsLine? See today's best NFL picks from SportsLine's R.J. White, who is on a 114-90-2 roll (+2078) on his last 106 NFL picks.